GCN2, active from DiscoverX

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GCN2, active

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Description

N-terminal GST-tagged recombinant, human GCN2 full length. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626. GCN2 (EIF2AK4) belongs to a family of kinases that phosphorylate the α subunit of eukaryotic translation initiation factor-2 (EIF2S1) to downregulate protein synthesis in response to varied cellular stresses